Fabrication of Gentamicin-Loaded Hydroxyapatite/Collagen Bone-Like Nanocomposite for Anti-Infection Bone Void Fillers
نویسندگان
چکیده
منابع مشابه
Hydroxyapatite/collagen bone-like nanocomposite.
Our group has succeeded to synthesize material with bone-like nanostructure and bone-like inorganic and organic composition via self-organization mechanism between them using simultaneous titration method under controlled pH and temperature. The hydroxyapatite/collagen (HAp/Col) bone-like nanocomposite completely incorporated into bone remodeling process to be substituted by new bone. Cells cul...
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Background: In the present study, a tissue engineered silk fibroin (SF) scaffold containing simvastatin-loaded silk fibroin nanoparticles (SFNPs) were used to stimulate the regeneration of the defected bone. Methods: At first, the porous SF scaffold was prepared using freeze-drying. Then simvastatin-loaded SFNPs were made by dissolvation method and embedded in the SF scaffold. Afterwards, the ...
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In recent years, nanoceramics have been used in scaffolds to emulate the nanocomposite with a three-dimensional structure of natural bone tissue. In this regard, polycaprolactone biopolymer is widely used as a scaffold in bone tissue engineering. The goal of this research is to produce porous scaffolds of polycaprolactone - zeolite biocomposite with suitable mechanical, bioactive and biological...
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Sepsis is a greatly feared complication of total joint arthroplasty. One key question is how to prevent perioperative bacterial adherence, and therefore the potential for infectious complications. The objective of our study was to appraise the emerging capacity of staphylococcal survival on prosthetic materials and to analyze the in vitro effects of gentamicin and vancomycin loaded polymethylme...
متن کاملCan Bone Void Fillers Carry Load? Behaviour of Calcium Phosphate Cements Under Different Loading Scenarios
Ajaxon, I. 2017. Can Bone Void Fillers Carry Load? Behaviour of Calcium Phosphate Cements Under Different Loading Scenarios. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1492. 67 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9865-8. Calcium phosphate cements (CPCs) are used as bone void fillers and as complements to hardware ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2020
ISSN: 1422-0067
DOI: 10.3390/ijms21020551